Purpose.

This Funding Opportunity Announcement (FOA), issued by the National Institute of Child Health and Human Development (NICHD), encourages Program Project Grant (P01) applications from institutions/organizations that propose to study the ways in which Assisted Reproductive Technologies (ART)

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may affect eggs, sperm and preimplantation embryos that could, in turn, lead to adverse outcomes during fetal development, the perinatal period, childhood, adulthood or even subsequent generations.

While most ART offspring appear to be healthy and developing normally, there are some reports of adverse outcomes and some concerns owing to the variety and type of ART protocols in use.

This FOA encourages applications on human subjects and animal models that can include a wide variety of basic, clinical and epidemiological approaches.

P01 applicants can take advantage of this FOA to propose multidisciplinary, interactive and synergistic program projects in order to address some of these issues.

It is anticipated that this FOA will provide empirical data for understanding ART outcomes and also how reproductive health is fundamental to overall health and quality of life.