Functional Genetics, Epigenetics, and Non-coding RNAs in Drug Addiction (R01)

Purpose.

Genetic and genomic studies have identified genes and gene variants that potentially modulate the fundamental biological mechanisms underpinning addictive processes.

Discovery of these genes/variants, while extremely valuable, is only a first step in understanding molecular mechanisms


of addiction.

This Funding Opportunity Announcement encourages basic functional genomic research in two areas:
1. functional validation to determine which candidate genes/variants/epigenetic/non-coding RNA features have an authentic role in addictive processes, and 2. detailed elucidation of the molecular pathways and processes modulated by candidate genes/variants, particularly for those genes with an unanticipated role in addiction.

Mechanism of Support.

This FOA will utilize the R01 mechanism and runs in parallel with FOAs of identical scientific scope, PA-11-034 , that encourages applications under the R21 mechanism and PA-11-035 that encourages applications under the R03 mechanism.

Funds Available and Anticipated Number of Awards.

Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary.

The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and costs of the applications received.

Related Programs

Adult Viral Hepatitis Prevention and Control

Department of Health and Human Services


Drug Abuse and Addiction Research Programs

Department of Health and Human Services


Agency: Department of Health and Human Services

Office: National Institutes of Health

Estimated Funding: Not Available


Relevant Nonprofit Program Categories

G02.13.02
Hepatitis
G02.13.03
HIV/AIDS




Obtain Full Opportunity Text:
http://grants.nih.gov/grants/guide/pa-files/PA-11-033.html

Additional Information of Eligibility:
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U. S. Territory or Possession.

Full Opportunity Web Address:
http://grants.nih.gov/grants/guide/pa-files/PA-11-033.html

Contact:
NIH OER WebmasterFBOWebmaster@OD.NIH.GOV

Agency Email Description:
If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

Agency Email:
FBOWebmaster@OD.NIH.GOV

Date Posted:
2010-11-16

Application Due Date:
2013-12-05

Archive Date:
2014-01-05


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