Neuroimmune Mechanisms Of Alcohol Related Disorders (R21)

This FOA issued by National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Institutes of Health (NIH), encourages Research Project Grant (R21) applications from institutions/organizations that propose to study the neuroimmune mechanisms of alcohol related disorders.

Studies using

credit: Nathan Rouse


animal models and post-mortem human alcoholic brains suggest that alcohol exposure has a significant impact on the neuroimmune system in the brain.

However, it remains unclear how the altered neuroimmune factors contribute to brain and behavioral changes associated with alcohol exposure.

Emerging data indicate that neuroimmune molecules are expressed in neurons and glia, and play an important role in modulating synaptic function, neurodevelopment, and neuroendocrine function.

These neuromodulatory properties, together with their essential roles in neuroinflammation, provide a new frame work to understand the role of neuroimmune factors in mediating neuroadaptation, neurodegeneration, and behavioral disorders due to alcohol exposure.

Studies supported by this FOA will provide fundamental insights of neuroimmune mechanisms underlying brain functional and behavioral changes induced by alcohol.

Related Programs

Alcohol Research Programs

Department of Health and Human Services


Agency: Department of Health and Human Services

Office: National Institutes of Health

Estimated Funding: Not Available


Relevant Nonprofit Program Categories





Obtain Full Opportunity Text:
http://grants.nih.gov/grants/guide/pa-files/PA-11-065.html

Additional Information of Eligibility:
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U. S. Territory or Possession.

Full Opportunity Web Address:
http://grants.nih.gov/grants/guide/pa-files/PA-11-065.html

Contact:
NIH OER WebmasterFBOWebmaster@OD.NIH.GOV

Agency Email Description:
If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

Agency Email:
FBOWebmaster@OD.NIH.GOV

Date Posted:
2010-12-08

Application Due Date:
2014-01-07

Archive Date:
2014-02-07



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