Deciphering the Impact of RNA Modifications on Brain Aging and AD/ADRD (R21 Clinical Trial Not Allowed)

The purpose of this Notice of Funding Opportunity (NOFO) is to catalyze innovative research to elucidate the molecular landscape and functional implications of RNA modifications in brain aging and Alzheimer's disease (AD) and AD-related dementias (ADRD).

AD-related dementias include Lewy

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body dementia (LBD), frontotemporal dementia (FTD), vascular cognitive impairment/dementia (VCI/D), and mixed dementias.This NOFO supports exploratory and developmental grant (R21) applications focused on uncovering novel mechanisms underlying RNA modification-mediated processes and their impact on brain aging and the pathogenesis of AD/ADRD.

Proposed studies should focus on functional characterization and mechanistic investigation of previously identified RNA modifications.

Related Programs

Aging Research

Department of Health and Human Services

Agency: Department of Health and Human Services

Office: National Institutes of Health

Estimated Funding: $350,000

Who's Eligible

State Governments

County Governments

City or Township Govenments

Special District Governments

Independent School Districts

Public and State Controlled Institutions of Higher Education

Native American Tribal Governments

Public Housing Authorities/Indian Housing Authorities

Native American Tribal Organizations (other than Federally recognized tribal governments)

Nonprofits having a 501 (c) (3) status with the IRS

Nonprofits that do not have a 501 (c) (3) status with the IRS

Private Institutions of Higher Education

For-profit organizations other than small businesses

Small Businesses

Others - see "Additional Information on Eligibility" for clarification

Relevant Nonprofit Program Categories

H01
Medical Research, General/Other

H03
Medical Disciplines & Occupations Research

H03.05
Geriatrics Research

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Obtain Full Opportunity Text:
https://grants.nih.gov/grants/guide/rfa-files/RFA-AG-25-023.html

Additional Information of Eligibility:
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U. S. Territory or Possession.

Full Opportunity Web Address:
http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-25-023.html

Contact:

Agency Email Description:
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

Agency Email:

Date Posted:
2024-07-31

Application Due Date:

Archive Date:
2024-12-07