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DoD Neurofibromatosis Clinical Trial Award
The NFRP Clinical Trial Award supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of NF.
Clinical trials may be designed to evaluate promising new products, pharmacologic agents (drugs or biologics), devices, clinical guidance, and/or emerging approaches and technologies.
Proposed projects may range from small proof-of-concept trials (e.g., pilot, first in human, phase 0) to demonstrate the feasibility or inform the design of more advanced trials through large-scale trials to determine efficacy in relevant patient populations.The vision of the FY23 NFRP is to decrease the clinical impact of NF.
Toward this end, the NFRP seeks to support innovative, high-impact research that will foster new directions for and address neglected issues in NF research; sponsor multidisciplinary and multi-institutional collaborations that will bring new perspectives to the field; promote translational and clinical studies to move promising ideas from bench to bedside; and develop a balanced portfolio of meritorious research related to all aspects of NF1, NF2, and Schwannomatosis.Areas of Emphasis:
The FY23 NFRP strongly encourages research applications that specifically address the critical needs of the NF community in one or more of the Areas of Emphasis listed below.
All applications are also encouraged to include materials and data from diverse populations in their research.• NF2 and Schwannomatosis-related areas (e.g., hearing, balance, schwannoma, ependymoma, meningioma, LZTR1, SMARCB1)• Endpoint validation, biomarker discovery, and technological innovation for assessments• Application of data science• Non-tumor manifestations not limited to:o Paino Cognitive manifestationso Sleep
Clinical trials may be designed to evaluate promising new products, pharmacologic agents (drugs or biologics), devices, clinical guidance, and/or emerging approaches and technologies.
Proposed projects may range from small proof-of-concept trials (e.g., pilot, first in human, phase 0) to demonstrate the feasibility or inform the design of more advanced trials through large-scale trials to determine efficacy in relevant patient populations.The vision of the FY23 NFRP is to decrease the clinical impact of NF.
Toward this end, the NFRP seeks to support innovative, high-impact research that will foster new directions for and address neglected issues in NF research; sponsor multidisciplinary and multi-institutional collaborations that will bring new perspectives to the field; promote translational and clinical studies to move promising ideas from bench to bedside; and develop a balanced portfolio of meritorious research related to all aspects of NF1, NF2, and Schwannomatosis.Areas of Emphasis:
The FY23 NFRP strongly encourages research applications that specifically address the critical needs of the NF community in one or more of the Areas of Emphasis listed below.
All applications are also encouraged to include materials and data from diverse populations in their research.• NF2 and Schwannomatosis-related areas (e.g., hearing, balance, schwannoma, ependymoma, meningioma, LZTR1, SMARCB1)• Endpoint validation, biomarker discovery, and technological innovation for assessments• Application of data science• Non-tumor manifestations not limited to:o Paino Cognitive manifestationso Sleep
Relevant Nonprofit Program Categories
Obtain Full Opportunity Text:
https://www.neh.gov/grants/education/humanities-connections
Additional Information of Eligibility:
Eligible Applicants Eligible applicants that can apply for this funding opportunity are listed below: • Nonprofit with 501C3 IRS status (other than institution of higher education) • Nonprofit without 501C3 IRS status (other than institution of higher education) • For-profit organizations (other than small business) • Small, minority, and women-owned businesses • Universities • Colleges • Research institutions • Hospitals • Community-based organizations • Faith-based organizations • Federally recognized or state-recognized American Indian/Alaska Native tribal governments • American Indian/Alaska native tribally designated organizations • Alaska Native health corporations • Urban Indian health organizations • Tribal epidemiology centers • State and local governments or their Bona Fide Agents (this includes the District of Columbia, the Commonwealth of Puerto Rico, the Virgin Islands, the Commonwealth of the Northern Marianna Islands, American Samoa, Guam, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau) • Political subdivisions of States (in consultation with States) • Non-domestic (non-U.S.) entity • Other
Full Opportunity Web Address:
https://www.neh.gov/grants/education/humanities-connections
Contact:
Agency Email Description:
CDMRP Help Desk
Agency Email:
Date Posted:
2023-05-22
Application Due Date:
Archive Date:
2023-09-24
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