The purpose of this initiative is to solicit new R01 applications that propose innovative studies to explore how exposures to environmental toxicants may inhibit, create new or otherwise impact epitranscriptomic crosstalks and provide mechanistic insights into how these interactions play a role in initiation,
credit:
progression, and/or exacerbation of adverse health outcomes.
Epitranscriptomic crosstalks are defined as interactions between epitranscriptomic marks and associated Readers Writers and Erasers (RWEs) and epigenomic marks and/or epigenomic RWEs, and genomic structures.