Purpose.

This Funding Opportunity Announcement (FOA) issued by the NIH Basic Behavioral and Social Sciences Opportunity Network (OppNet) solicits Research Project Grant (R01) applications from institutions and organizations that propose to investigate the mechanistic pathways linking psychosocial

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stressors and behavior.

This research will facilitate investigation of multiple and potentially bidirectional pathways underlying the link between psychosocial stressors and behaviors that may ultimately impact biological function, health, and disease.

Applicants are encouraged to use model systems and longitudinal approaches to design innovative and integrative studies to elucidate how psychological factors, social factors, and environments impact the processes by which stressors are coupled with and influenced by various behaviors.

Applications examining moderating factors such as individual demographic (age, gender/sex, ethnicity) and psychological (vulnerabilities, resilience) differences, risk factors, early exposure, and environments (including toxicants) are desirable.

This research will provide a deeper understanding of the psychological, environmental, and social processes that ultimately connect psychosocial stress to behaviors, physiological processes, health, and disease.

Mechanism of Support.

This FOA will utilize the R01 award mechanism.

Funds Available and Anticipated Number of Awards.

OppNet intends to commit approximately $1,325,000 million in total costs (Direct plus Facilities and Administrative [F&A] costs) in FY 2011 to fund 2-3 new grants in response to this FOA, pending the number and quality of applications and availability of funds.