Purpose.

This FOA issued by the NIH Basic Behavioral and Social Sciences Opportunity Network (OppNet) solicits Research Project Grant (R21) applications from institutions and organizations that propose to develop and test conceptually-based and comprehensive measures of psychosocial stress that

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can be applied across species and across the lifespan.

Applicants submitting proposals under this FOA are encouraged to incorporate variations in exposures, chronicity, environments (including toxicants and social environments), cognitions, and responses, as well as capture important factors for measuring stress in both humans and animals, in men and women, and across the lifespan.

Such studies should demonstrate that the measures, coupled with appropriate bridges between laboratory and population-based designs, advance our understanding of the components of psychosocial stressors that are most relevant to disease, and provide comparability across studies.

Mechanism of Support.

This FOA will utilize the R21 award mechanism.

Funds Available and Anticipated Number of Awards.

OppNet intends to commit approximately $1,050,000 million in total costs (Direct plus Facilities and Administrative [Fand A] costs) in FY 2011 to fund 4-6 new grants in response to this FOA, pending the number and quality of applications and availability of funds.

A period of up to 2 years of funding may be requested.

Applicants should budget travel expenses for Principal Investigators (PIs) to attend one 2-day meeting of FOA grantees per year.