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The Cooperative Re-Engagement Controlled Trial (CoRECT)
HIV antiretroviral therapy (ART) can durably suppress the plasma HIV viral load which restores and preserves immunologic function.
Effective ART improves individual survival and quality of life and dramatically reduces further HIV transmission making it a priority for both individual health and community public health.
Within the United States, the largest lost opportunity to achieve a suppressed viral load occurs among individuals who have failed linkage to or retention in HIV medical care.
Health department demonstration projects have suggested that good partnerships and information exchange between health departments and HIV clinics are essential to linkage/re-engagement programs.
The Cooperative Re-Engagement Controlled Trial (CoRECT) will evaluate an intervention to identify HIV-infected persons who are out-of-care and engage them in HIV care.
Health department laboratory surveillance data and clinic appointment data will be shared at monthly case conferences to define recent out-of-care HIV infected individuals.
These individuals will be randomized to receive an active health department field services intervention or usual linkage and engagement in care services.
The active intervention activities will include field services to locate, contact, and provide assistance, including a same-day appointment to access HIV medical care.
CoRECT will evaluate if the active intervention resulted in increased re-engagement in care, retention in care, and HIV viral load suppression as compared with usual linkage and engagement in care services.
Ultimately the trial will demonstrate the feasibility of a joint health department clinic intervention to identify recently out-of-care individuals and the effectiveness of an active health department intervention to (re-)engage these individuals in HIV medical care.
Effective ART improves individual survival and quality of life and dramatically reduces further HIV transmission making it a priority for both individual health and community public health.
Within the United States, the largest lost opportunity to achieve a suppressed viral load occurs among individuals who have failed linkage to or retention in HIV medical care.
Health department demonstration projects have suggested that good partnerships and information exchange between health departments and HIV clinics are essential to linkage/re-engagement programs.
The Cooperative Re-Engagement Controlled Trial (CoRECT) will evaluate an intervention to identify HIV-infected persons who are out-of-care and engage them in HIV care.
Health department laboratory surveillance data and clinic appointment data will be shared at monthly case conferences to define recent out-of-care HIV infected individuals.
These individuals will be randomized to receive an active health department field services intervention or usual linkage and engagement in care services.
The active intervention activities will include field services to locate, contact, and provide assistance, including a same-day appointment to access HIV medical care.
CoRECT will evaluate if the active intervention resulted in increased re-engagement in care, retention in care, and HIV viral load suppression as compared with usual linkage and engagement in care services.
Ultimately the trial will demonstrate the feasibility of a joint health department clinic intervention to identify recently out-of-care individuals and the effectiveness of an active health department intervention to (re-)engage these individuals in HIV medical care.
Related Programs
Epidemiologic Research Studies of Acquired Immunodeficiency Syndrome (AIDS) and Human Immunodeficien
Department of Health and Human Services
Agency: Department of Health and Human Services
Office: Centers for Disease Control and Prevention
Estimated Funding: $6,900,000
Office: Centers for Disease Control and Prevention
Estimated Funding: $6,900,000
Obtain Full Opportunity Text:
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Additional Information of Eligibility:
The following organizations are eligible to apply: Competition is limited to state, local, and territorial health departments that are independently funded by CDC to perform HIV surveillance or their Bona Fide Agents.
Funding decisions may also consider geographic diversity (e.g., applications that increase the diversity of geographic regions defined by the Department of Health and Human Services (http://www.hhs.gov/about/regionmap.html) represented in the program in order to maximize the programs flexibility in addressing evolving public health research needs related to HIV that may vary by geographic region.
Competition is further limited to health departments who meet the three special eligibility criteria listed in Section III.3 below.
3.
Special Eligibility Requirements: a.
Applicants must have complete HIV laboratory reporting of CD4 and viral load test results, defined as follows3: i.
The jurisdictions laws/regulations require the reporting of all CD4 and viral load results to the state/city health department ii.
A minimum of 95% of HIV-related test results from laboratories that perform HIV-related testing for each area are being reported to the state/city health department iii.
The jurisdiction is reporting at least 95% of all CD4 and viral load test results to CDC as of this applications deadline date.
b.
Applicants may not be a grantee of The Care and Prevention in the United States (CAPUS) Demonstration Project (FOA # CDC-RFA-PS12-1210), information available at: http://www.cdc.gov/hiv/prevention/demonstration/capus/index.html c.
Applicants must have more than 10,000 adults and adolescents living with diagnosed HIV infection, year-end 2010, in their jurisdiction based on estimates in CDCs HIV Surveillance.
Report available at: http://www.cdc.gov/hiv/library/reports/surveillance/index.html As of July 19, 2013, the eligible states are Massachusetts, Michigan, New York (excluding New York City), South Carolina, and Washington.
The eligible local health departments are the District of Columbia, Los Angeles County, New York City, Philadelphia, and San Francisco (Table 1).
State and local health departments are responsible for and have authority to conduct HIV surveillance and to provide linkage to HIV medical care for all HIV-infected individuals within their jurisdiction.
Eligibility for this FOA is limited to state and local health departments because a critical component of this study includes the use of state and local health depart
Full Opportunity Web Address:
THIS IS NOT AN ACTIVE LINK. PLEASE CLICK ON THE WORDS "FULL ANNOUNCEMENT" AT THE TOP OF THIS PAGE.
Contact:
CDC Procurement and Grants Office (PGO)Technical Information Management Section (TIMS)Phone: 770-488-2700
Agency Email Description:
TECHNICAL INFORMATION MANAGEMENT SECTION (TIMS)
Agency Email:
pgotim@cdc.gov
Date Posted:
2013-11-18
Application Due Date:
2014-01-16
Archive Date:
2014-02-15
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