The purpose of this Notice of Funding Opportunity (NOFO) is to develop multi-organ automated microphysiological systems (MPS) for studying the effects of microgravity conditions on human body in low Earth orbit at the International Space Station National Laboratory (ISS-NL).
This program will
provide insights on human patho(physiology), especially aging-related functional decline and age-related diseases.
The multi-organ MPS configuration will allow better modeling of the whole organism.
Improved automation with extended longevity of MPS will facilitate longer experiments in space and the collection of more physiologically relevant data.
The inclusion of samples representing the broad spectrum of diversity in the human population will allow for better modeling of aging progression and development of interventions.