Small Business Grants from the




Department of Health and Human Services
 $62,853,680,968 Department of Transportation
 $56,443,571,981 Environmental Protection Agency
 $35,751,587,496 Department of Energy
 $24,661,368,000 National Aeronautics and Space Administration
 $14,032,768,821 Department of Homeland Security
 $13,986,266,741 Department of Labor
 $10,348,285,755 Department of Defense
 $10,111,366,675 Department of the Interior
 $9,806,569,960 Department of Agriculture
 $8,296,397,040 Agency for International Development
 $7,754,781,106 Department of Commerce
 $6,871,103,950 Department of Housing and Urban Development
 $6,642,477,476 Department of State
 $6,042,666,916 Department of Justice
 $5,571,395,802 Department of Education
 $2,642,831,221 Department of the Treasury
 $1,019,380,000 Other Agencies
 $724,036,487


Utilizing Real-World Data and Algorithmic Analyses to Assess Post-Market Clinical Outcomes in Patients Switching Amongst Therapeutically Equivalent Complex Generic Drug Products and Reference Listed Drugs (U01) Clinical Trial Not Allowed
Complex generic drug products represent an increasing share of the generic marketplace and may have distinct user interface differences compared to reference listed drug (RLD) products. A modernized...more
Posted On - 2024-01-15


Developing PBPK Model-Based Mechanistic IVIVCs for Long Acting Injectable Suspensions and Implants (U01) Clinical Trial Optional
The objective of this research proposal is to develop physiologically based pharmacokinetic (PBPK) model-based mechanistic in vitro in vivo correlations (IVIVCs) for two major types of long acting...more
Posted On - 2024-01-15


Evaluating the Cutaneous Pharmacokinetics of Topical Drug Products Using Pharmacokinetic Tomography (U01 Clinical Trial Required)
The purpose of this funding opportunity is to support the research and development necessary to advance non-invasive (e.g., quantitative tomography-based) technologies, including the development of...more
Posted On - 2024-01-15




Integrating Machine Learning with Computational Fluid Dynamics Models of Orally Inhaled Drug Products (U01) Clinical Trials Not Allowed
Computational fluid dynamics (CFD) has played a crucial role in providing an alternative bioequivalence (BE) approach for generic orally inhaled drug products (OIDPs), in addition to comparative...more
Posted On - 2024-01-15


Synthesis and Biological Activity Assessment of Different Diastereomers in siRNA Drug LEQVIO (Inclisiran) (U01) Clinical Trial Not Allowed
The purpose of this research is to systematically evaluate the diastereomeric composition of LEQVIO (Inclisiran), an FDA-approved, N-acetyl galactosamine (GalNAc)-conjugated siRNA drug, and to...more
Posted On - 2024-01-15


Identification of Drug-related and Formulation-Related Factors that Result in Alcohol Dose Dumping of Modified Release Oral Drug Products (U01) Clinical Trial Not Allowed
Modified release (MR) oral drug products are considered to have a high risk for alcohol dose dumping (ADD) because they contain large quantities of drug(s), designed to release over a prolonged...more
Posted On - 2024-01-15


NHGRI Technology Development Coordinating Center (U24 Clinical Trial Not Allowed)
This Notice of Funding Opportunity (NOFO) encourages applications for renewal of the NHGRI Technology Development Coordinating Center (TDCC). The TDCC will continue to provide an infrastructure for...more
Posted On - 2024-01-12




Rehabilitation Engineering Research Centers (RERC) Program: RERC on Rehabilitation Strategies, Techniques, and InterventionsThe purpose of the RERC program is to improve the effectiveness of services authorized under the Rehabilitation Act by conducting advanced engineering research on and development of innovative...more
Posted On - 2024-01-11


Solutions to Enable Regional Genomic Medicine eConsult Services (R43/R44 Clinical Trial Optional)
The purpose of this notice of funding opportunity (NOFO) is to support applications from small businesses to develop solutions for commercialization that enable regional genomic medicine eConsult...more
Posted On - 2024-01-09









Featured Government Grant Resources


Community Development Credit Unions

A Community Development Credit Union, more commonly known as a CDCU, is a credit financial institution which owned and controlled by its members in an effort to sustain the ability of being able to provide a wide array of financial services.







Department of Agriculture: Value Added Producer Grants

The Value-Added Producer Grants program is geared towards helping the Independent Producers of Agricultural Commodities, Agriculture Producer Groups, Farmer and Rancher Cooperatives, and Majority-Controlled Producer-Based Business Ventures in developing techniques that would create marketing opportunities and establish business plans involving viable marketing opportunities that involve the production of bio-based products from agricultural commodities.


Chief executive of HCT, Dai Powell, shares the experiences and practical lessons he learned along the way when teaming up with Ealing Community Transport to deliver site transport during the Olympic Park construction.






More Federal Domestic Assistance Programs


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