Effect of Physicochemical Properties of Ophthalmic Formulations on Ocular Bioavailability Program
Page 2

Furthermore, it is also noted that suitable bioequivalence methods are lacking for many generic ophthalmic formulations, including suspensions and emulsions. Therefore an investigation of the relationship between various physicochemical properties and their effect on ocular bioavailability will help the FDA in establishing guidelines for the determination of bioequivalence of ophthalmic suspensions and emulsions.

The scope of the program will cover two types of inquiries:

a) In vitro study – Formulations with different physicochemical properties are manufactured using a selected steroid and characterized in vitro. Drug release and stability tests are conducted to understand how differences in physicochemical properties may affect ocular bioavailability.

b) In vivo study – Formulations selected based on the results of the in vitro study are tested in an animal model. A pharmacokinetic study should be conducted by assessing the ocular distribution of the steroid in various eye tissues and organs at various time points.

In order to support these initiatives, the Food and Drug Administration is set to administer funds in the amount of $400,000.

The institutions and organizations who will be deemed eligible to submit an application under this program are the following:

a) Private and Public Non-profit entities

b) State and Local Governments

c) Indian Tribal Governments and Organizations

d) Faith-based Organizations

e) Community-based Organizations

f) Institutions of Higher Education

g) Private and Public Colleges and Universities

h) Independent School Districts

The United States Department of Health and Human Services, the mother agency funding the Effect of Physicochemical Properties of Ophthalmic Formulations on Ocular Bioavailability Program, is country's premiere agency for protecting the health of all Americans and providing essential human services, especially to those who medically challenged and vulnerable.

Effect of Physicochemical Properties of Ophthalmic Formulations on Ocular Bioavailability Program
  Back to Page 1

About The Author Iola Bonggay is an editor of TopGovernmentGrants.com one the the most comprehensive Websites offering information on government grants and federal government programs. She also maintains Websites providing resources on environmental grants and grants for youth programs.

Additional Government Grants Resources

Biodemography of Aging Program
The National Institutes of Health has formed a partnership with the National Institute on Aging (NIA) in an effort to establish the Biodemography of Aging Program wherein they intend to solicit applications with the intent to conduct research studies regarding demographic and life-science approaches that could potentially expand the current understanding of aging, frailty and mortality.

---

Urban Waters Small Grants Program
The United States Environmental Protection Agency has recently constituted the development of the Urban Waters Small Grants Program wherein it seeks to solicit project proposals from eligible applicants who wish to contribute to the improvement of water quality in urban areas.

---

Choosing An Online Private College And University
Private colleges and Universities are known for their high standards and excellent academic programs. Their online programs are no different. If you are ready to get your Bachelor's degree, or if you...

---

Summer Seminars and Institutes Program
The National Endowment for the Humanities has recently established the Summer Seminars and Institutes Program wherein it aims to provide support to faculty development programs in the field of the humanities for school, college, and university teachers.

---

Financing Your Education - Work Study Opportunities
The Federal Work-Study Program assists those undergraduate postsecondary students that cannot afford their educational expenses without financial assistance by providing them with part-time employment. Not only does the Federal Work-Study Program provide part-time employment, it also encourages these students to participate in community service activities.

---

First Time Homebuyer Programs in Virginia
In 1972, the Commonwealth of Virginia has constituted the establishment of the Virginia Housing Development Authority in an effort to respond to the needs of Virginians who seek quality, affordable housing.

---

What You Need to Know About the Grants Policy Committee
The Chief Financial Officers Council, one of the largest federal agencies that works towards collaboratively improving the process of financial management in the United States Government, has established the Grants Policy Committee(GPC).

---