Exfoliated Cells and Circulating DNA in Cancer Detection and Diagnosis (R21)

Purpose.This funding opportunity announcement (FOA), issued by the National Cancer Institute (NCI), invites applications aimed at the development of novel technologies for capturing, enriching, and preserving exfoliated abnormal cells from body fluids or effusions as well as methods for concentrating

credit:


the tumor-derived sub-cellular material for use in biomarker studies.

In body fluids, such as sputum, exfoliated tumor cells are a minor component compared to normal cells.

As a result, the detection of exfoliated abnormal cells by routine cytopathology is often limited by the low number of atypical cells present in a given specimen.

New enrichment methods are necessary to facilitate the detection of very low levels of exfoliated tumor cells and tumor-derived sub-cellular materials in biological fluids.



Mechanism of Support.

This FOA will use the NIH Exploratory/Developmental (R21) grant mechanism.



Funds Available and Anticipated Number of Awards.

Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary.

The total amount awarded and the number of awards will depend upon the mechanism, numbers, quality, duration, and costs of the applications received.



Related Programs

Cancer Cause and Prevention Research

Department of Health and Human Services


Cancer Detection and Diagnosis Research

Department of Health and Human Services


Agency: Department of Health and Human Services

Office: National Institutes of Health

Estimated Funding: Not Available


Relevant Nonprofit Program Categories





Obtain Full Opportunity Text:
http://grants.nih.gov/grants/guide/pa-files/PA-09-238.html

Additional Information of Eligibility:
Other Eligible Applicants include the following:
Eligible Agencies of the Federal Government; Hispanic-serving Institutions; Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; U. S. Territory or Possession.

Full Opportunity Web Address:
http://grants.nih.gov/grants/guide/pa-files/PA-09-238.html

Contact:
NIH OER WebmasterFBOWebmaster@OD.NIH.GOV

Agency Email Description:
If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

Agency Email:
FBOWebmaster@OD.NIH.GOV

Date Posted:
2009-07-22

Application Due Date:
2012-09-07

Archive Date:
2012-10-08


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